Management

simecka

Jerry W. Simecka


Executive Director

Jerry received his Ph.D. in microbiology from the University of Alabama in Birmingham, and eventually became a Research Assistant Professor. In 1995, he joined the Department of Microbiology at University of North Texas Health Science Center. He is currently a Professor and Chair of the Department of Molecular Biology and Immunology. His research is focused on respiratory disease and immunity using in vivo models of infections and vaccination. In addition, research on biofilm infections is ongoing. In collaboration with Cumbre Pharmaceuticals Inc, Dr. Simecka’s lab established several in vivo models of infections and pharmacokinetic/ pharmacodynamic analysis for discovery research. His expertise also includes analysis of immune function, mucosal immunity and immunization. He has authored over 60 manuscripts and book chapters, is a member of several grant review panels, and a past Chair of Division G of the American Society for Microbiology.

bill weiss

William J. Weiss


Director

Bill was previously Director of Drug Evaluation at Cumbre Pharmaceuticals Inc. where he was responsible for animal efficacy models, pharmacology and all pre-clinical microbiology research and development efforts focused on the discovery and development of new antimicrobial agents. Prior to this, he was a Group Leader in Infectious Disease Discovery Research at Wyeth Research, Lederle Laboratories and Schering-Plough, holding various positions of responsibility in antibacterial, antiviral and antifungal discovery research for over 34 years. His responsibilities included leading in vitro and in vivo evaluation of novel compounds from medicinal synthetic and natural products chemistry. He has worked on numerous antibacterial programs including the development of the marketed antibiotics; Suprax, Zosyn and Tygacil. His expertise encompasses the development of animal research models, the evaluation of compounds in those animal models as well as pharmacokinetic / pharmacodynamic analysis. He has authored / co-authored over 90 research presentations and journal articles.

pulse

Mark E. Pulse


Assistant Director

Mark holds a Masters of Science degree in molecular microbiology and immunology, and his research at the University of North Texas Health Science Center has primarily been focused on bacterial pathogenesis and pre-clinical drug evaluation within in vivo models. For the last 5 years he has been directly involved in the development of several in vivo models that have included GI- and respiratory-associated infectious diseases, device-associated (biofilm) infections, and pharmacokinetic studies within multiple animal species. He also has experience with survival surgery in multiple animal species, including USDA species. In addition to in vivo research, his in vitro work has involved the use of multiple molecular techniques to determine important virulence pathways associated with Staphylococcus aureus infections.

This page last updated 03rd Jul 2014