- The discovery and development of novel estrogen-based neuroprotectants for the treatment of Alzheimer’s disease and other age-related disorders
- Assessment of 17 alpha-estradiol for longevity and vigor during aging
- Assessment of the uses of methylene blue for treatment of a variety of neurodegenerative diseases
- The assessment of dietary intervention on stroke, Alzheimer’s disease and other neurodegenerative conditions
Core translational Laboratories
- Drug Synthesis Core- a collaboration between the UNT Health Center and the Washington University to synthesize and pre-clinically assess novel drugs for effectiveness in Alzheimer’s disease.
- Mitochondrial Functional Assessment Core-a multiple capacity core for the assessment of the effectiveness of drugs in improving mitochondrial function.
- Animal Behavioral Assessment Core- an animal core that assesses the effects of aging and Alzheimer’s disease on cognition-related behaviors and evaluated the intervention by diets and drugs.
- Electrophysiology Core- a core that evaluated the effects of aging and diet/drug intervention on function of the hippocampus, the memory area of the brain.
- Alzheimer’s Disease Brain Bank-a facility that solicits, collects, evaluates and stores brains from Alzheimer’s disease persons and cognitively normal controls for distribution to researchers.
- Health & Aging Brain Among Latino Elders (HABLE)- explores aging among Mexican Americans in Texas. Studying healthy and unhealthy aging in the Mexican American culture will allow us to create better interventions and treatment programs. Participation may include blood draw, medical record review and interview. Current enrollment is limited to men and women age 50 and older.
- Health & Aging Brain Study- is a new research project at UNTHSC to better understand the biological and lifestyle factors that influence memory and thinking as we age. We are making special efforts to find community members with Alzheimer’s disease, memory complaints or diabetes to participate in our research. Participation may include blood draw, medical record review and interview. Current enrollment is limited to people age 50 and older.